Clinical Experience of Traumatic Cervical Syndrome Treated with Daisaikoto / 日本東洋医学雑誌

We administered daisaikoto to 13 patients with traumatic cervical syndrome and observed complete responses in the following 2 patients. Patient 1 was a 40-year male. He was in the xiaoyang stage, and showed high abdominal tension and marked chest oppression. These findings were indications for daisaikoto. Patient 2 was a female in her 50 s. She was in the xiaoyang stage, showed moderate abdominal tension and chest oppression, and was aware of chest tension and constipation. Evaluation using the VAS in the 13 patients showed a complete response in 3 patients, partial response in 6, minor response in 1 and no response in 3. To clarify indications for daisaikoto in this disease, findings of Japanese Oriental Medicine in the 13 patients were evaluated. Of 9 patients with high abdominal tension, 8 showed partial or complete responses. Of 4 patients with moderate abdominal tension, a complete response, partial response, and no response were observed in 1, 1, and 2, respectively. In addition, objective abdominal coldness was present in both patients with moderate abdominal tension who showed no response but not in the patient showing a complete response.We confirmed the importance of therapy based on oriental medical syndromes when daisaikoto is used for traumatic cervical syndrome. However, patients with moderate abdominal tension without abdominal coldness can be differentiated from others for this therapy.

A Case of Idiopathic Chronic Fatigue Successfully Treated with Sansonintokagen / 日本東洋医学雑誌

Chronic fatigue is a common symptom in primary health care and caused by various organic and functional diseases. Although improvement is attained by controlling underlying organic disease, it is sometimes difficult to relieve fatigue in patients with chronic fatigue syndrome or dysthymia. We have encountered patients with idiopathic chronic fatigue (ICF) successfully treated with sansonintokagen. A 62-year-old female complained of chronic fatigue several years after menopause, and had normal status in routine blood and image analyses at a nearby hospital. Her condition was diagnosed as ICF with sleeplessness. Treatment with sansonintoaogibakumondo for 8 weeks improved her chronic fatigue and sleeplessness, and enabled her to continue housekeeping. This observation suggests that this kampo formula may be a useful agent for ICF.

A Case of Serous Gonarthritis with Nonproductive Cough Successfully Treated with Eppikajutsuto / 日本東洋医学雑誌

We report a case of serous gonarthritis with nonproductive cough successfully treated with Eppikajutsuto. A 37-year-old Japanese man developed a right genicular arthrocele with nonproductive cough, in October X. Over 100 ml of serous synovial fluid was drained via an arthrocentesis puncture procedure. Although he was treated with nonsteroidal anti-inflammatory agents by an orthopedist, under a diagnosis of serous gonarthritis, his symptoms did not improve. Laboratory findings suggested inflammatory conditions (serum CRP 3.4 mg/dl, ESR 76 mm/h). At the time of his first visit in January X+1, orthopedic examinations revealed that rheumatoid arthritis was unlikely, based on negative physical and laboratory findings. A contrast MRI knee joint scan did not demonstrate any tumor-like mass of synovium which would indicate pigmented villonodular synovitis. And orthopedists found it difficult to specify the cause of his serous gonarthritis. After a common cold in December X, cough stimulated by cold exposure was superimposed on serous gonarthritis.We utilized Eppikajutsuto under the interpretation that both his genicular arthrocele and nonproductive cough were due to a “sui” disturbance. This Eppikajutsuto therapy reduced his genicular arthrocele and nonproductive cough in1month. His symptoms and inflammatory reactions were completely improved in 3 months, regardless of gradual withdrawal of his medication.

Consideration to Clinical Indication of Boiogito / 日本東洋医学雑誌

Boiogito, which has been used for obesity, edema and arthritis by using flabby constitution as a clinical indication, is mentioned in Jin Kui Yao Lue (Synopsis of the Golden Chamber). We experienced five cases of wind-wetness syndrome or edema caused by the pathogen Wind successfully treated with boiogito. There were common findings in these cases, i.e., heavy sweating or perspiration while sleeping, chilly feelings and worsening of the evening subjective symptoms and pulse diagnoses, such as floating, string-like and congested pulse in objective findings. On the basis of these cases, we investigated the efficacy of boiogito extract in 10 patients having the all of common findings mentioned above. As a result, boiogito improved symptoms in 8 patients. This suggests that medical examination by interview and distinctive pulsation are important in deciding the Kampo diagnosis for boiogito.

A Case of Jugular Sense of Discomfort with Dryness and Nonproductive Cough Successfully Treated with Soshikokito / 日本東洋医学雑誌

We report a case with an intractable jugular sense of discomfort, with dryness and nonproductive cough successfully treated with soshikokito. A 62-year-old Japanese man developed jugular sense of discomfort with dryness and nonproductive cough, after odontotherapy in October. Although he was treated with Western drugs by an otolaryngologist, under the diagnosis of xerostomia with no mechanical problems, his symptoms did not disappear. The symptoms followed a protracted course, and he further developed a loss of appetite. At the time of first visit in October, otorhinolaryngological studies showed no structural lesions or problems, with the exception of minimum salivation in the normal range on a gum test. There was no evidence of dry eyes. With the diagnosis of xerostomia, Bakumondoto-go-hangekobokuto was administered for a month but showed no sign of improvement. Making a shift to bukuryoin-go-hangekobokuto regained his appetite, but did not produce any improvement on dryness. We then utilized soshikokito under the interpretation that both dryness and nonproductive cough is ki-gyaku. The soshikokito therapy reduced his dryness in a month's time. Additionally, his nonproductive cough gradually decreased, and within 11 months after, he had no symptoms, regardless of a gradual medication withdrawal.

Investigation of Clinical Indications of Hangekobokuto / 日本東洋医学雑誌

Hangekobokuto, on the basis of Jin-kui-yao-lue, has been used to treat acute and chronic gastric disease, psychiatric disorders, abnormal sensation in the throat, and edema which gives the feeling of a small food particle obstructing the throat. We experienced 2 cases involving a sense of incongruity in the interscapular region (pain and/or stiffness), which were successfully treated with hangekobokuto extract.On the basis of these first cases, we investigated the efficacy of hangekobokuto extract in 15 patients having both “ki-utsu” and “suitai”, and a sense of incongruity (pain and/or stiffness) in the interscapular region, without the throat-obstructive feeling of a small in-situ food particle.Improvements in complaints were observed in all patients, with a reduction or disappearance of their sense of incongruity in the interscapular region. Thus, it is possible that hangekobokuto could be widely applicable where symptoms of tenderness or a sense of incongruity in the interscapular region occur (especially the sides of the spinous process of thoracic vertebrae 4-7), in addition to the previously documented indications (heart burn, epigastric discomfort and abdominal fullness).

Two Cases of Fibromyalgia Syndrome Succesfully Treated with Kampo Medicine / 日本東洋医学雑誌

We demonstrated two patients with fibromyalgia syndrome (FMS), successfully treated with Kampo medicine, and considered the resemblance between the clinical manifestation of FMS and SHO for Kanzo-bushi-to.The first case was a 52-year-old women who consulted a local hospital in 2001 due to althralgia and myalgia in the left hand, bilateral elbows, shoulders and foot. Her condition was diagnosed as FMS without abnormal findings in the thorough medical examination. Treatment with NSAIDs was not effective, so she consulted our department in 2004. She was treated with Keishi-ni-eppi-itto-ka-ryojutsu-ka-boi-ogi-kakkon. After two mouths, her symptoms had reduced to 50% by visual analog scale (VAS). By March 2006, her symptoms had significantly decreased to 20% by VAS and NSAIDs became unnecessary.The second case was a 58-year-old woman who had suffered from tolerable pain in her right elbow for 10 years. In 2004, she visited the Department of Orthology at her local hospital due to pain in the neck, bilateral arms and shoulders. There were no findings on cervical X-ray or neurological examination, and NSAIDs were administered. Her symptoms did not resolve, therefore, she consulted our department in 2005. She was diagnosed with FMS, based on fulfilling the diagnostic criteria for FMS of ACR (American college of rheumatology) in 1990. She was treated with Kanzo-bushi-to. After 3 months, her symptoms had reduced to 30% by VAS. By Mar. 2006, her pain had redused to 25% by VAS and she was physically fit enough for a daily life.

Clinical Indications of Jiinshihoto / 日本東洋医学雑誌

The source of Jiinshihoto, which has been used for patients troubled by chronic cough with Ki obstruction, is Wanbinhuichun. We report on 8 cases with various chronic inflammatory diseases in the airway successfully treated with Jiinshihoto. They had similar symptoms, i. e., chronic coughing both dry and moist, and the abnormal sensations in the throat. Our experience with these cases suggests that tympanitic sound on right half side of the abdomen increase the accuracy of Jiinshihoto usage.

Four Cases of Symptoms with Dryness in the Throat Successfully Treated with Hyakugokokinto / 日本東洋医学雑誌

We prescribed Hyakugokokinto for four patients suffering from dryness in the throat. Dry throat improvements were observed in all patients, while improvements in insomnia were observed as well. Thus, insomnia may be a further indication for the use of Hyakugokokinto.

Investigation of Clinical Indications of Choyoto based on 9 Effective Cases / 日本東洋医学雑誌

Choyo-to, which has long been used for acute and chronic intestinal disease, dermatological disorders and pulmonary abscess, is attributed to the writings of 7th Century physician Sun Simiao, known as the “Qian-jinyao-fang”. We have also successfully treated nine different patients suffering from various diseases, using Choyo-to. In most of these cases, patients complained of constipation. Thus far, our modern experience suggests that Choyo-to may be indicated for not only right-side pain upon naval palpitation, pressure sensation at the ileocecum and excessive strain of abdominal muscles, but also for cases of dry skin, edematous skin and tendency of normal tongue color.

Two Cases of Allergic Rhinitis Successfully Treated with Shimbuto / 日本東洋医学雑誌

We experienced 2 cases of allergic rhinitis successfully treated with Shimbuto. Shoseiryuto, Goreisan and Ryokankyomishingeninto did not have any favorable effect on these cases. They had similar subjective symptoms, that is, a mass of nasal mucus, became cold easily and developed taste for citrus fruits. There were common objective symptoms, such as, fullness of the upper abdomen, coldness of the epigastrium, epigastric throbbing pulsation and a fluid sound in the stomach upon palpation. These findings suggest that Shimbu-to might be practicable for the patients who did not received the blessing of the standard Kampo therapy.

Study of Shuchi-Bushi, a Powder Type of Aconiti Tuber after being Autoclaved, Especially Concerning Side Effects-Usage and Dosage of Shuchi-Bushi from This Study- / 日本東洋医学雑誌

<i>Aconitum carmichaeli</i> debeaux is an essential herbal medicine that possess anti-inflammatory, analgesic, and cardiotonic effects. Five hundred ninety-three subjects were treated with Shuchi-bushi (a powder type of this aconiti tuber that has been autoclaved) added to Kampo extract granules, between the years 1996 and 2002. The patient population consisted of 153 men and 440 women with an average age of 54.5 years. Four patients showed adverse reactions such as hypertension, nausea and hot flashes with Shuchi-bushi. There were no serious adverse effects, and the toxic symptoms disappeared quickly by reducing the Shuchi-bushi dosage, or cessation.<br>Shuchi-bushi has been used in small quantities because of its highly toxic alkaloids. However, this study indicates that Shuchi-bushi can be used more actively.

The Influence of Kampo Medicine on the Disease Activity in Forty-three Patients with Rheumatoid Arthritis / 日本東洋医学雑誌

During a four-year period from 1994 to 1998, we treated 46 cases of rheumatoid arthritis (RA) with Kampo medicine. Clinical disease activity of RA was assessed using the Lansbury activity index (L. I.). After a year of treatment with Kampo medicine, 20 patients showed over 75% improvement by L. I Eleven cases were considered to be non-responders. Twenty-six cases out of 37 who had been treated with Western medicine were able to discontinue using, or reduce reliance upon, analgesic drugs and steroid hormones following Kampo treatment. Steinbrocker's functional classification of RA was improved from 2.3 to 1.8.<br>We used Aconiti Tuber for 40 patients, and 13 cases showed aconiti poisoning. Two cases represented adverse reactions to Astragali Radix.<br>In this study, Boi-ogi-to-ka-bushi was the most effective for RA, and Keishi-ka-ryo jutsubu-to was the second most effective. Efficacy of Boi-ogi-to was enhanced with large quantities of Sinomeni Caulis et Rhizoma and Astragali Radix. We mixed Boi-ogi-to with Keishi-ka-ryo jutsubu-to when Keishi-ka-ryo-jutsubu-to did not work well. RA is one of the representative diseases that respond to Kampo medicine.

Case Reports of Kampo Treatment on Acute Cholecystitis or Cholangitis in the Long-term Bedridden Patients / 日本東洋医学雑誌

In all but a few cases, the treatment for elderly patients must be conservative owing to the unavoidably poor general condition of the patients.<br>We report on three cases of long-term bedridden patients with acute cholecystitis or cholangitis who were effectively treated with Kampo prescriptions. An 86-year-old male with choledecholithiasis and acute cholangitis responded to Inchin-ko-to. When he repeatedly relapsed after the discontinuance of Kampo treatment, Inchin-ko-to was effective, and Inchin-shingyaku-to successfully improved his general condition. In an 89-year-old male with acute cholecystitis, Dai-saiko-to extracts and Bukuryo-shigyaku-to were effective. An 88-year-old female with cholecystolithiasis and acute cholecystitis responded to Dai-saiko-to and Bukuryo-shigyaku-to.<br>Most elderly patients are Inkyo-sho (Yin-deficient). But, when they are suffering from acute sickness, it is important to treat them according to the principle of “Senkyukokan (treating acute symptoms before treating chronic internal symptoms).” The severe sickness is treated first, and then the mild phase of the disease is treated.

The Correlation Between Signs of Kampo Medicine and Visceral Fat Obesity / 日本東洋医学雑誌

Visceral fat obesity is closely associated with lifestyle-related diseases that include symptoms such as hypertension, diabetes mellitus, hyperlipidemia, etc. To examine the correlation between pulse, appearance of tongue, and abdominal palpation-diagnostic indicators according to Kampo medicine-and visceral fat obesity, we investigated 209 subjects who received health screenings, and obtained the following results. 1) The simply obese subjects, as determined by body mass index, showed symptoms of excess state, Kidepression, and stasis of body fluids according to the diagnostic techniques of Kampo medicine. 2) The visceral fat-rich subjects were diagnosed by means of abdominal ultrasonography and showed symptoms of pulsus maximum and Oketsu (blood stasis) state.

Four Cases Report of Intractable Pressure Ulcers Effectively Treated with Kigi-kenchu-to-ka-bushi / 日本東洋医学雑誌

Four intractable decubitus ulcer patients who had not responded to any Western medicine were treated effectively with Kigi-kenchu-to-ka-bushi. Case 1 was a 82-year-old female patient who had been admitted due to multiple-cerebral infarction. She had been bedridden and suffered repeatedly from pressure ulcers. Her bed sores were controlled successfully with Kigi-kenchu-to-ka-bushi. After treatment by Kigi-kenchu to-ka-bushi, any decubitus ulcer was not recurrence. Case 2 was a 85-year-old female patient. The pressure ulcer was 2cm in diameter and extent of soft tissue fissure underlying it was about 10cm in diameter. Skin color around pressure sore changed to purple. After administration of Kigi-kenchu-to-ka-bushi, skin color returned to normal and decubitus ulcer recovered. Case 3 was a 59-year-old male patient who had undergone operation on an intractable decubitus ulcer with fistula, but he did not get well. Two weeks later, after treatment with Kigi-kenchu-to-ka-bushi, he felt pain when we sterilized his ulcer. It was thought to be a sign of improvement of the wound. Physical status became better as the ulcer healed. Case 4 was a 64-year-old female patient with brain death because of acute myocardial infarction. Her pressure ulcer was treated effectively with Kigi-kenchu-to-ka-bushi, too.

The Correlation Between Pulse, Tongue and Abdominal Palpation Signs as Measured by Kampo Medicine Diagnostic Techniques / 日本東洋医学雑誌

To clarify the correlation between pulse, appearance of the tongue and abdominal palpation signs as measured by Kampo medicine diagnostic techniques, we investigated 488 cases who received health screening. In addition we investigated the effects of smoking and drinking alcohol on pulse, tongue and abdominal palpation signs, and also the correlation between the findings of blood biochemical tests, and the pulse and appearance of the tongue, and obtained the following results.<br>1) In normal pulse the abdominal power and the tension of lower abdominal wall elevate, and the subjective palpitations of the upper umbilicus and the fluid sound in the stomach upon palpation were faint.<br>2) In elevated pulse abdominal power increased and the subjective palpitations of the lower umbilicus were faint.<br>3) As the oppressive pain on bilateral area near the umbilicus increased, the petechia often occurred.<br>4) The epigastric throbbing pulsation over epigastric region showed the positive correlation with transverse dehiscence.<br>5) Positive correlation was shown between the oppressive pain on the left area near the umbilicus and the purple tongue coating.<br>6) Smokers are apt to have red or purple tongue and tend to show yellow, thick, or ? residue-like (_??__??_) tongue coating. During abdominal palpation the positive correlation was shown between the frequency of smoking and the tonus of the left rectus abdominis muscle.<br>7) The amount of drinking alcohol and the abdominal power show positive correlation, and negative correlation with the subjective palpitations of the upper umbilicus.<br>8) The value of hemoglobin and hematocrit were often increased when a red tongue coating, purple tongue coating, petechia or a thick tongue coating were shown, and were decreased in ? emaciation (_??__??_).<br>9) The value of amylase showed a negative correlation with the red, thick, ??_??__??_, ? residue-like (_??__??_) tongue coating.

Case Report of Bukuryo-shigyaku-to / 日本東洋医学雑誌

Literature on Bukuryo-shigyaku-to describes it as “those who perspire, have diarrhea, do not recover from disease and are afflicted by restlessness.” In this study we examined 4 cases where the administration of Bukuryo-shigyaku-to had an effect, where complaints which accompanied autonomic disorder and psychoneurosis brought about by automobile accidents were diagnosed as restlessness. With the experience of these cases and consideration of the literature, we consider the following to be appropriate states of illness for the administration of Bukuryo-shigyaku-to in psychoneural sicknesses.<br>1) states of illness where conditions of psychological introversion caused by such things as fear, heart palpitations, and depression exist, and it is necessary to lift spirits.<br>2) states of illness where such Ki-depressions as whole body weariness and lack of appetite exist.3) states of illness where such stasis of body fluids as dull headache and dizziness exist.<br>4) where epigastric region tenderness and abdominal palpitations exist.

The Correlation Between Abdominal Palpation Signs of Kampo Medicine and Laboratory Data / 日本東洋医学雑誌

There have been few studies on the relationship between the body mass index (BMI), complete blood cell count, blood chemistry, fatty liver evidence and Kampo abdominal palpation signs. This study was designed to clarify the above points. It involved 484 subjects who had undergone full physical examinations. The results of this study, can be summarized as follows:<br>1. Abdominal tension (traditionally referred to as “fukuryoku”) was related to BMI (males and females), TG, TCh/HDL, GPT, RBC, Hb and evidence of fatty liver (males) and corresponded negatively with HDL (males).<br>2. Tonus of the rectus abdominis muscle (“fukuhikokyu”) was negatively related to BMI (males).<br>3. The sound of gurgling liquid in the stomach (“shinsuion”) was negatively related to BMI (males and females).<br>4. Palpitations of the abdominal aorta in the upper abdomen (“shinkaki”) was related toHDL (males) and negatively related to BMI (males and females).<br>5. Palpitation of the abdominal aorta below the navel (“saikaki”) was negatively related to BMI (males).

The Correlation Between Abdominal Palpation Signs of Kampo Medicine and Anatomical and Physiological Findings of the Cardio-respiratory System / 日本東洋医学雑誌

There have been few studies of the relationship between respiratory function, chest x-rays, electrocardiograms, and the abdominal palpation signs of Kampo medicine. This investigation was designed to elucidate the above points with 489 subjects who had undergone a full physical examination. As a result of this study, we make clear the following features:<br>1. Abdominal tension (traditionally referred to as “fukuryoku”) was related to vital capacity, lateral distance of the thorax, CTR, counter-clockwised axis deviation of QRS, and negatively related to the intra-vertical thoracic distance.<br>2. Sound of gurgling fluid in the abdomen (“Shinsuion”) was related to intravertical distance of the thorax, clockwise axis deviation of QRS, negatively related to the lateral distance of the thorax, width of the heart and CTR.<br>3. Tonus of the rectus abdominis muscles was related to vital capacity and intravertical distance of the thorax and negatively related to the lateral distance of the thorax.<br>4. Palpitation of the abdominal aorta (traditionally called “Shinkaki”, “seijouki”, and “saikaki”) revealed nega tive correlation to the lateral distance of the thorax and width of the heart.<br>5. Resistance or tenderness upon pressure in the epigastric resion (“shinkahiko”) was negatively related to the intrathoracic distance.<br>6. Resistance resembling a string of pearls in the midline of the lower abdomen (“seichushin”) was related to intravertical distance of the thorax, clockwise axis deviation of QRS, and negatively related to SV 1 electro cardiogram voltage.